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Lorem ipsum dolor sit amet consectetur adipiscing elit. Quisque faucibus ex sapien vitae pellentesque sem placerat. In id cursus mi pretium tellus duis convallis. Tempus leo eu aenean sed diam urna tempor. Pulvinar vivamus fringilla lacus nec metus bibendum egestas. Iaculis massa nisl malesuada lacinia integer nunc posuere. Ut hendrerit semper vel class aptent taciti sociosqu. Ad litora torquent per conubia nostra inceptos himenaeos.
| Therapy Area | Modality | Target/MOA | Indication | Target Val | Hit ID | Lead ID | Lead Op | DC Nom | Investigator |
| Oncology | Small Mol | Mut-KRAS pathway | KRAS-mutant tumors | Kelley | |||||
| Biologic | IL13RA2,EGFRvIII | GBM | Balyasnikova | Small Mol | MYC | Solid tumors | Abdulkadir | ||
| PROTAC | Dot1L | ALL | Abdulkadir | ||||||
| Small Mol | PLEK2 | MDS | Ji | ||||||
| Small Mol | UBE3A | HPV+HNSCC | Kiyokawa | ||||||
| Cell Tx | CAR-T Platform | Liquid tunors | Shukla | Small molecule | TDO2 | Uterine Fibroids | Bulan | Data Platform | Target ID | Solid tumors | Raman |
| Inflammation & Immunology | Nanoparticle | mTOR | T1D and autoimmune | Scott | |||||
| Peptide | KLC1c | Cardiac IRI | Muller | Small Mol | Synthetic melanin | Radiation dermatitis | Gianneschi | ||
| Platform | NFkB/IRF | Vaccine reactogencity | Esser-Kahn | ||||||
| Small Mol | CLDN2 | IBD | Weber | ||||||
| Rare disease | Gene Tx | COL7A1 | RDEB | Wu | |||||
| Small molecule/td> | TNNI3 | Hypertrophic CM | Goldspink | ||||||
| Neuroscience | Small molecule | KALRN | Fragile X Syndrome | Penzes | |||||
| Platform | Target ID | Rett Syndrome | Kozorovitsky |
Current Portfolio Projects
